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LAROTRECTINIB VITRAKVI : Cost/Price, Dosage/Doses, Uses, Side Effects, Warnings etc. information

Generic LAROTRECTINIB / Brand VITRAKVI 25mg / 100mg Capsule is a targeted therapy categorized as a "Tropomyosin Receptor Kinase Inhibitor". larotrectinib / Vitrakvi medicine is prescribed for treating solid tumors that express neurotrophic receptor tyrosine kinase (NTRK) gene fusions.

What are the international reference brand names of Generic drug larotrectinib? The actual Generic Drug and Base Medicine LAROTRECTINIB is sold internationally under the most common marketing brand(s) VITRAKVI. See our lowest larotrectinib Vitrakvi cost / prices at the top of this page.

What is the brief overview information on Generic larotrectinib / Brand Vitrakvi ? Targeted therapy is a therapy of about 100 years of research dedicated in clarifying the difference between normal cells and cancer cells. Cancer treatment mainly focuses on killing dividing cells as cancer cells divide rapidly. Well, some of our normal cells also divide rapidly. They cause multiple side effects tothe body. This therapy also identifies many other features of cancer cells. Many scientists have searched for a type of medicine that kills cancer cells without damaging normal cells. All the targeted therapy works in a pattern to interfere with the feature of cancer cells to divide, repair, and communication with other cells. The targeted therapies are divided into 3 types. Some of the therapies focus on the ongoing internal component of the cancer cells. Some therapies work in small molecules of the cancer cell to prevent them into the body. TSeveral types of therapies are focusing in the inner part of the cell and some are focusing on its outer layer. Some therapies consist of receptors of the cells which are called monoclonal antibodies. Anti-angiogenesis is focusing on vessels to provide oxygen which causes the cells to starve. Scientists clarify that targeted therapies are not the replacement of traditional therapies. They can be used combining with each other. More therapies are also occurring to identify what type of cancer can be treated by this. Larotrectinib is a therapy of specific region that focuses in binding to TRK (tropomycin receptor kinase) proteins which are mostly found on the cell. TRK proteins over express through tumors or develop active TRK proteins. The binding of proteins of Larotrectinib, the pathway that promotes the tumor cells is prompted.

What is the Branded Drug Vitrakvi / Generic larotrectinib used for (Indications) ? • The Treatment of solid tumors can be expressed as NTRK (neurotrophic receptor tyrosine kinase) gene fusions. Note: Once a drug has been approved for one use then the physicians can elect to use this same drug for solving any other problems only if they think that it can be helpful.

When should Vitrakvi / larotrectinib medication not to be used (Contraindications) ? Information not available, sorry.

What’s the prescribed larotrectinib Vitrakvi dosage / dosing requirement? Information not available, sorry.

What to do if Generic larotrectinib / Brand Vitrakvi dosage is missed ?

What are the Brand Vitrakvi / Generic larotrectinib drug / pills uses? • This medication is available in capsules of 25 mg to 100 mg and also as an oral solution. • Take this medicine as per the guidance of your healthcare provider. • If you have side-effects then your healthcare provider may stop your dose. Do not change your dose or stop taking this medication until your healthcare provider allows you to do so. • Larotrectinib should be taken by mouth with water or food. • It is taken two times a day. • Swallow the whole tablet. The capsules are not to be crushed or chewed. • Ask your doctor or pharmacist to clarify your doubts about how to correctly measure and give a dose of this solution. • Always use the oral syringes provided with the medicine to make sure that the measurement of the prescribed dose is correct. Each oral syringe may be used over a period of 7-days. Make sure not to use a household teaspoon to measure the dose. • If you forget to take a dose then try to take it as soon as you can. If you reach the scheduled time of your next dose then skip the dose you missed. • Try to avoid eating grapefruit and its juice while taking the medicine. The amount of larotrectinib that you will receive depends on plenty of factors which include general health, or other health problems. and any other medicine you are administering

What are the Vitrakvi larotrectinib warnings and precautions before use ? • Before starting your treatment inform your doctor necessary information which includes the information of prescription, vitamins, herbal remedies, etc. • Always avoid eating grapefruit or its juice during the treatment with larotrectinib. • Don't try to drive a car or operate machinery • If you are pregnant or planning for pregnancy then inform your health care professional before starting this treatment. This medicine can harm your baby. • Before starting the treatment, your doctor may do your pregnancy test. • For women: Use effective birth control (contraception) during treatment and for at least 1 week after the final dose of larotrectinib. • After using this medicine it is advisable not to breastfeed till one week..

What are larotrectinib Vitrakvi side effects ? Important things which should be remembered about the side effects of this medicine:- • Side effects are predictable according to its duration. • There are many options which are very helpful to minimize the side effects. • The relationship between the presence or severity of the side effects and effectiveness of this medicine is none. • It is not necessary that every patient experiences all the symptoms which are listed. • Side effects of this medicine are manageable. There are many options to minimize the effect or prevent the effects of larotrectinib. The side-effects which are listed below are seen among 30% of the patients who are taking larotrectinib: • Neurotoxicity includes the symptoms such as delirium (acutely disturbed state of mind), speaking difficulty (dysarthria), dizziness in body, difficulty while walking, and abnormal sensations like tingling in the body, prickling, burning, chilling, numbness (paresthesia) - These symptoms mostly occur in the first 3 months of treatment. You should keep yourself away from tasks which involve mental alertness like driving and/ or operating heavy machineries. Low count of red blood cells , this can increase the chances of getting anemia. • You may also experience tiredness and fatigue while taking this medicine. • You may experience Hypoalbuminemia. • Increase in the level of liver enzymes (hepatotoxicity) - this mostly occurs in patients who're undergoing the treatment of larotrectinib since 2 months. These symptoms return to normal once treatment is stopped.

What are the other Brand name Vitrakvi / Generic larotrectinib Vitrakvi warnings and precautions? If you experience any of these symptoms then immediately consult your healthcare provider. • If you're having temperature of 100.4º F (38º C) or higher • Other symptoms like wheezing in the body, Shortness in your breath, facing difficulty in breathing, closing up of the throat, and swelling of facial. The following symptoms are not very serious but if these occur then inform your healthcare provider. • • Vomiting (4-5 times in every 24 hours) • Diarrhea (4-6 episodes in 24 hours) • Syoccurreatigue (when unaboccurredry self-care activities) • Yellowing of skin and eyes, light-colored stools, dark urine, and/or stomach pain • Heavy swelling in the arms, legs, feet, or in ankles. • Symptoms of infection such as fever, chills, etc. • Difficulty in speaking, mind confusion, memory weakness, tremors, or frequent episodes of dizziness or falls • Burning, numbness, or tingling feeling • High blood pressure:- Severe headache, dizziness, passing out, and changes in eyesight if you experience any unusual symptoms then immediately inform your healthcare provider.

What are larotrectinib Vitrakvi medication interactions with other drugs? Information not available, sorry.

What are the storage conditions of Brand Name Vitrakvi / Generic Drug larotrectinib? Information not available, sorry.

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The above information has been sourced from U.S. NATIONAL LIBRARY OF MEDICINE , is intended only to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

Vitrakvi - larotrectinib : Package Insert / Prescribing Information Leaflet, Medication Guides & Instructions for Use

Patient Package Inserts (PPI), Medication Guides (MG), and Instructions for Use (IFU) are paper handouts that come with many prescription medicines. The guides address issues that are specific to particular drugs and drug classes, and they contain FDA-approved information that can help patients use the medicine safe and effectively and try to avoid serious adverse events. Not all medicines have patient information and if you have questions about your medicines you should always talk with your Healthcare Provider or Pharmacist.

Medication Guides are developed by the manufacturer, approved by the FDA, and required to be given to consumers each time the medication is dispensed. You may see a printable pdf copy of the Medication Guide / Patient Information Leaflet of Vitrakvi - larotrectinib in English Arabic Bulgarian Chinese Dutch Filipino French Hebrew Japanese Korean Portuguese Romanian Russian Spanish Swedish Thai Turkish Vietnamese

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